At SIGNAL 2025, Twilio’s opening keynote served as a declaration of intent. CEO Khozema Shipchandler opened the session with a bold statement: “We are facing the end of the customer experience as we know it.” That set the tone for a forward-looking address centered around one major theme: the shift from generic digital interactions to deeply contextual, data driven, AI-powered engagement.

Twilio is not just evolving its product suite. It is transforming into an orchestration layer for real-time, personalized communications across the customer lifecycle. With 2.5 trillion digital interactions delivered last year, the company is using that scale to frame its next act: delivering true context at scale.
This marks a continuation of Twilio’s vision to empower builders—developers, data teams, and CX professionals—with the tools they need to create intelligent, scalable customer journeys. But it also signals a broader trend in the communications space: CPaaS alone is no longer enough. Context is the currency of the next generation of customer engagement.
Microsoft Partnership Paves the Way for Enterprise AI
A major highlight of the keynote was the formal announcement of a multi-year strategic partnership with Microsoft. This alliance centers around integrating Twilio’s customer engagement stack with Microsoft Azure AI Foundry, allowing developers to build multimodal, cross-channel AI agents that plug directly into business workflows.

Microsoft CEO Satya Nadella joined Shipchandler via a pre-recorded fireside chat. Nadella described the current moment as the convergence of multiple S-curves—from generative AI to cloud economics—and emphasized the need for contextually aware systems. Azure AI brings scalability and governance. Twilio brings the data and communications layer. Together, they aim to enable organizations to reimagine customer service, marketing, and sales with AI at the core.
The strategic move also reflects a growing trend among organizations to seek platform interoperability. By enabling customers to use Azure credits for Twilio services, both companies are addressing procurement friction while providing a launchpad for joint innovation in agentic AI.
The Power of Contextual AI
A consistent refrain throughout the keynote was the importance of contextual AI. Inval Shani, Twilio’s Chief Product Officer, summed it up succinctly: “The only AI that actually matters today is contextual AI.”
Twilio’s future hinges on the combination of customer identity, real-time engagement data, and predictive models. Through its unified profile API, the platform is evolving to power experiences that are anticipatory rather than reactive.
Case in point: the partnership with Chelsea FC. By harnessing behavioral data, location, and fan preferences, the football club is able to deliver targeted offers, messages, and content the moment a fan enters the stadium. This allows Chelsea FC to send the right message, at the right moment, with the right context.
Twilio calls this shift “moving from segment-level personalization to individual-level orchestration.” The long-term goal is for agents (both human and AI) to understand customer journeys not as linear paths but as living data models that update in real time and across channels.
Real-Time Profiles and Unified Data
At the center of Twilio’s product evolution is the concept of the real-time customer profile. This is where Twilio’s heritage in communications and its acquisition of Segment truly intersect. The goal is to unify identity and engagement data to deliver smarter, consent-based personalization.
These profiles are designed to include dynamic attributes like churn propensity, best time to send, and content preferences. They allow AI systems, whether built by Twilio or its customers, to generate insights and trigger interactions that feel natural and timely.
With compliance top of mind, Twilio emphasized that customer data remains under business control. This stance is likely to resonate with organizations concerned about data privacy and model training risks in LLM ecosystems.
Twilio also showcased expanded observability features that let organizations track when and how engagement happens. These insights feed directly into models that adapt to changes in user behavior, market conditions, or business logic.
Trust, Simplicity, and Scale
Twilio closed the keynote with a renewed commitment to its three platform pillars: trust, simplicity, and intelligence. During Cyber Week, Twilio hit 100 percent uptime across its channels. A data point the company proudly shared to reinforce its reliability.
Developers, often short on time and spread across multiple responsibilities, want building blocks that just work. Twilio is leaning into that expectation, offering what it calls prefab solutions rather than a raw API toolbox. The platform is becoming simpler to navigate, easier to integrate, and more intelligent by design.
This effort includes unified authentication across all Twilio products, new compliance tooling like the TCPA toolkit, and advances in agent orchestration. These changes reduce friction for builders, support global compliance, and improve time to value.
A Platform Built for Builders
The SIGNAL 2025 keynote offered more than just product updates. Twilio did a great job at showcasing its strategic reset for Twilio’s identity: One Twilio. The company is making a clear play to become the intelligent communications layer in an AI-driven enterprise stack.
By marrying contextual data with scalable AI and developer-first tools, Twilio is positioning itself not just as a CPaaS provider, but as an essential part of modern customer experience infrastructure. The message to its 10 million developers and 335,000 customers was clear: This is a platform built by builders, for builders, and for the future of engagement.
With AI adoption accelerating, Twilio’s emphasis on contextuality, compliance, and developer experience may very well define what’s to come for customer engagement. CXaaS anyone? SIGNAL 2025 wasn’t about flashy features or AI-washing the event. It was about rearchitecting the very infrastructure that powers meaningful customer relationships.

